9. Suissa S, Dell’Aniello S, Ernst P. Long-term natural history of chronic obstructive pulmonary disease: severe exacerbations and mortality. Thorax. 2012;67(11):957–963. doi: 10.1136/thoraxjnl-2011-201518.
10. Melles, M.C., et al. “The cost impact of informal care for patients with COPD and exacerbations in the Netherlands.” American Journal of Respiratory and Critical Care Medicine, vol. 211, no. Abstracts, May 2025, https://doi.org/10.1164/ajrccm.2025.211.abstracts.a3256.
11. PMC, Europe. Europe PMC, europepmc.org/article/PMC/4334315. Accessed 31 Oct. 2025.
12. Chen S, Kuhn M, Prettner K, et al. The global economic burden of chronic obstructive pulmonary disease for 204 countries and territories in 2020-50: a health-augmented macroeconomic modelling study. Lancet Glob Health. 2023;11(8):e1183-e1193. doi: 10.1016/S2214-109X(23)00217-6
13. Koff PB, Min SJ, Freitag TJ, et al. 2021. Impact of Proactive Integrated Care on Chronic Obstructive Pulmonary Disease. Chronic Obstr Pulm Dis 8(1): 100-16
14. Government Expenditure on Health – Statistics Explained – Eurostat, ec.europa.eu/eurostat/statistics-explained/index.php?title=Government_expenditure_on_health. Accessed 31 Oct. 2025.
15. Hunter LC, Lee RJ, Butcher I, et al. Patient characteristics associated with risk of first hospital admission and readmission for acute exacerbation of chronic obstructive pulmonary disease (COPD) following primary care COPD diagnosis: a cohort study using linked electronic patient records. BMJ Open. (2016) 6:e009121.
16. Ipsos (2025) Data on file: Global Policymakers’ Perspectives on COPD | Survey of Attitudes and Perceptions – Wave 2 Final Report (conducted on behalf of Global Allergy and Airways Patient Platform).
17. Rehman AU, Hassali MAA, Muhammad SA, et al. The economic burden of chronic obstructive pulmonary disease (COPD) in Europe: results from a systematic review of the literature. Eur J Health Econ. 2020;21:181–94.
18. Agarwal D. COPD generates substantial cost for health systems. Lancet Glob Health. 2023;11:e1138-9.
19. Løkke A, Lange P, Lykkegaard J, et al. Economic Burden of COPD by Disease Severity – A Nationwide Cohort Study in Denmark. Int J Chron Obstruct Pulmon Dis. 2021;16:603-613. doi: 10.2147/COPD.S295388
20. Jones PW et al. (2022). The Development of a COPD Exacerbation Recognition Tool (CERT) to Help Patients Recognize When to Seek Medical Advice. International Journal of Chronic Obstructive Pulmonary Disease, 17, 213‑222. DOI: 10.2147/COPD.S337644.